Russian Facility

One year later, in February 2003, Wesker infiltrated the Russian Umbrella Facility around the same time that Chris and Jill, his former S.T.A.R.S. subordinates, arrived for the purpose of destroy T-A.L.O.S., Umbrella's final B.O.W., and bring Umbrella to justice. Wesker made his way through the bowels of the facility teaming with all of its B.O.W.s, until reaching the sub-levels and encountering Sergei Vladimir once again, who claims that all the problems Umbrella went through over the years only made him stronger. Wesker told Sergei to step aside, and in response, Sergei sends his two Ivan bodyguards to dispatch Wesker. Using his superhuman abilities, Wesker defeated the two Ivans effortlessly, and continued deeper into the facility, where he met and confronted Sergei in the control room at the same time Chris and Jill fought T-A.L.O.S.. While they managed to eliminate Umbrella's final B.O.W., Wesker himself managed to defeat and kill Sergei Vladimir, who had mutated into a monster as a result of infecting himself with the t-virus. Wesker then took Umbrella data from the Red Queen, before deleting the computers memory, shutting down the facility. Shortly thereafter, finally having strong evidence against Umbrella, he brought his findings to the court. With information from Wesker (who operated under the pretence of being a personal friend of the CEO), Umbrella was found guilty and officially shut-down, its top officials suffering legal troubles and an international manhunt began for Ozwell E. Spencer. With the accumulated Umbrella Archives in hand, Wesker had what he needed to create a new Umbrella of his own. Wesker then took the archives and uploaded them to the system within his operations center, having accessibility to all of Umbrella's history and files at his fingertips. He vowed to one day meet Spencer again and succeed him as the one destined to usher in the new future of the world, which Spencer's vision, whatever it had been, failed to accomplish.
Soon after the raid on the Caucasus Facility, Wesker contacted Tricell; another pharmaceutical corporation, and with the wealth of information and resources collected from Umbrella, allowed Tricell to establish a secret bioweapons division, for which Wesker was greatly compensated. He decided to secretly work with them, as they were another valuable asset, and began further independent activities kept secret from his Organization superiors. A particular interest of Wesker was Excella Gionne, an employee of Tricell and descendant of its founders. Her intellect and ambitious nature, matching Wesker's own, caught his eye. He decided that she would serve as a high-level asset, and with his resources provided, he helped her climb through the ranks of Tricell. Excella found Wesker intriguing as well, to the point of romantic attraction. Due to his callous personality, Wesker did not return this affection, seeing Excella as a mere tool. However, he did not outright let her know this, playing along with her to an extent.